Cancer Genomics and Epigenetics

This is a branch of genomics which deals with the genomic content of the host. How the genomes in the host affect the carcinogenesis and what will happen if simple changes occur in these, what can be done to prevent this from happening or to cure the same.

The entire DNA contained in your cells makes up your genome. In many cells, the genome is bundled into two arrangements of chromosomes: one set each from the parents. These chromosomes are made out of six billion individual DNA letters. In the English letter set, there are 26 letters: A through Z. In the letters in order of our qualities, there are four letters: A, C, G and T. Much the same as the letters in a book make words to recount a story, so do the letters in our genomes. Genomics is the investigation of the grouping of these letters in your DNA and how each series of letters passes data to enable every cell in your body to work legitimately.

In tumor cells, little changes in the hereditary letters can change what a genomic word or sentence implies. A changed letter can make the cell make a protein that doesn't enable the cell to fill in as it should. These proteins can influence cells to develop rapidly and cause damage to the neighboring cells. By concentrating on the cancer genome, researchers can find what letter changes are making a cell turn into a disease. The genome of a tumor cell can likewise be utilized to reveal to one sort of tumor from another. Sometimes, considering the genome in a disease can help distinguish a subtype of growth inside that compose, for example, HER2+ breast tumor. Understanding the malignancy genome may likewise enable a researcher to choose the best treatment for every patient.

  • Track 1-1 Functional Studies of the Cancer Genome and Epigenome
  • Track 2-2 The Genetics and Epigenetics of Immuno-Oncology
  • Track 3-3 Computational Approaches to Cancer Genetics and Epigenetics
  • Track 4-4 The Cancer Epi-Transcriptome
  • Track 5-5 Genome-Wide Studies of Epigenetics and Cancer

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